Brand  (β version)

PDB ID: 3AGV

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Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
BMA Beta-D-mannopyranose PoSSuM
FUL Beta-L-fucopyranose PoSSuM
GAL Beta-D-galactopyranose PoSSuM
GLA Alpha-D-galactopyranose PoSSuM
MAN Alpha-D-mannopyranose PoSSuM
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose PoSSuM
NDG 2-acetamido-2-deoxy-alpha-D-glucopyranose PoSSuM
: Polysaccharide
Non-standard Residues
Code Name Show
CFZ 2'-deoxy-2'-fluorocytidine 5'-(dihydrogen phosphate)
UFT 2'-deoxy-2'-fluorouridine 5'-(dihydrogen phosphate)
Glycosylation
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Modification
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Structure summary

Code : 3AGV   PDBj   RCSB PDB   PDBe
Header : Immune System/RNA
Title : Crystal structure of a human IgG-aptamer complex
Release Data : 2010-11-10
Compound :
mol_id molecule chains synonym
1 Ig gamma-1 chain C region A,B IgG
fragment: Fc fragment, residues 120-330
mol_id molecule chains
2 5'-R(*GP*GP*AP*GP*GP*(UFT)P*GP*(CFZ)P*(UFT)P*(CFZ)P*(CFZ)P*GP*AP*AP*A*GP*GP*AP*AP*(CFZ)P*(UFT)P*(CFZ)P*(CFZ)P*A)-3' S,U
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
mol_id organism_scientific
2
synthetic: yes
Authors : Nomura, Y., Sugiyama, S., Sakamoto, T., Miyakawa, S., Adachi, H., Takano, K., Murakami, S., Inoue, T., Mori, Y., Nakamura, Y., Matsumura, H.
Keywords : IgG, RNA Aptamer, Immune System-RNA complex
Exp. method : X-RAY DIFFRACTION ( 2.15 Å )
Citation :

Conformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complex

Nomura, Y.,Sugiyama, S.,Sakamoto, T.  et al.
(2010)  Nucleic Acids Res.  38 : 7822 - 7829

PubMed: 20675355
DOI: 10.1093/nar/gkq615

Reaction

Chain : A, B
UniProt : P01857 (IGHG1_HUMAN)
Reaction : -