Brand  (β version)

PDB ID: 3AE6

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Ligands
Code Name Style Show Link
EPH L-alpha-phosphatidyl-beta-oleoyl-gamma-palmitoyl-phosphatidylethanolamine PoSSuM
F3S Fe3-s4 cluster PoSSuM
FAD Flavin-adenine dinucleotide PoSSuM
FES Fe2/s2 (inorganic) cluster PoSSuM
HEM Protoporphyrin ix containing Fe PoSSuM
JMP 2-{[3-(1-methylethoxy)phenyl]carbamoyl}benzoic acid PoSSuM
SF4 Iron/sulfur cluster PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 3AE6   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Title : Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid
Release Data : 2011-02-09
Compound :
mol_id molecule chains synonym
1 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial A Flavoprotein subunit of complex II, Fp
ec: 1.3.5.1
mol_id molecule chains synonym
2 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial B Iron-sulfur subunit of complex II, Ip
ec: 1.3.5.1
mol_id molecule chains synonym
3 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial C Succinate-ubiquinone oxidoreductase cytochrome B large subunit, CYBL
mol_id molecule chains synonym
4 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial D Succinate-ubiquinone oxidoreductase cytochrome b small subunit, CybS, Succinate-ubiquinone reductase membrane anchor subunit, QPs3, CII-4, Succinate dehydrogenase complex subunit D
fragment: residues 57-159
Source :
mol_id organism_scientific organism_common
1 Sus scrofa  (taxid:9823) Pig
organ: heart
tissue: muscle
mol_id organism_scientific organism_common
2 Sus scrofa  (taxid:9823) Pig
organ: heart
tissue: muscle
mol_id organism_scientific organism_common
3 Sus scrofa  (taxid:9823) Pig
organ: heart
tissue: muscle
mol_id organism_scientific organism_common
4 Sus scrofa  (taxid:9823) Pig
organ: heart
tissue: muscle
Authors : Harada, S., Sasaki, T., Shindo, M., Kido, Y., Inaoka, D.K., Omori, J., Osanai, A., Sakamoto, K., Mao, J., Matsuoka, S., Inoue, M., Honma, T., Tanaka, A., Kita, K.
Keywords : respiratory complex II, inhibitors, Electron transport, Iron, Iron-sulfur, Metal-binding, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Transit peptide, Transport, Tricarboxylic acid cycle, Heme, Transmembrane, FAD-binding protein, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 3.400 Å )
Citation :

Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid

Harada, S.,Sasaki, T.,Shindo, M.  et al.
To be Published 

Reaction

Chain : A
UniProt : Q0QF01 (SDHA_PIG)
Reaction: EC: Evidence:
Physiological Direction:
a quinone + succinate = a quinol + fumarate 1.3.5.1 PubMed:15989954
-
Chain : B
UniProt : Q007T0 (SDHB_PIG)
Reaction: EC: Evidence:
Physiological Direction:
a quinone + succinate = a quinol + fumarate 1.3.5.1 UniProtKB:P21912
-
Chain : C
UniProt : D0VWV4 (C560_PIG)
Reaction : -
Chain : D
UniProt : A5GZW8 (DHSD_PIG)
Reaction : -