Brand  (β version)

PDB ID: 2Z9K

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Ligands
Code Name Style Show Link
DMS Dimethyl sulfoxide PoSSuM
DOZ (dimethylamino)(hydroxy)zinc' PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 2Z9K   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Complex structure of SARS-CoV 3C-like protease with JMF1600
Release Data : 2007-12-25
Compound :
mol_id molecule chains synonym
1 3C-like proteinase A,B 3C-like protease
ec: 3.4.22.-
Source :
mol_id organism_scientific expression_system
1 SARS coronavirus  (taxid:227859) Escherichia coli  (taxid:562)
Authors : Lee, C.C., Wang, A.H.
Keywords : complex, ATP-binding, Cytoplasm, Endonuclease, Exonuclease, Helicase, Hydrolase, Membrane, Metal-binding, Nuclease, Nucleotide-binding, Nucleotidyltransferase, Protease, Ribosomal frameshift, RNA replication, RNA-binding, RNA-directed RNA polymerase, Thiol protease, Transferase, Transmembrane, Zinc, Zinc-finger
Exp. method : X-RAY DIFFRACTION ( 1.85 Å )
Citation :

Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.

Lee, C.C.,Kuo, C.J.,Hsu, M.F.  et al.
(2007)  Febs Lett.  581 : 5454 - 5458

PubMed: 17981158
DOI: 10.1016/j.febslet.2007.10.048

Reaction

Chain : A, B
UniProt : P59641 (multiple entry names are found)
Reaction : -