PDB ID: 2Y7Z
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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C0Z | 6-chloro-N-[(3s)-1-[(1s)-1-dimethylamino-2,3-dihydro-1h-inden-5-yl]-2-oxo-pyrrolidin-3-yl]naphthalene-2-sulfonamide | PoSSuM | |||
CA | Calcium ion | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 2Y7Z
Structure summary
Code : | 2Y7Z PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | BLOOD CLOTTING | ||||||||||||||||||||||||
Title : | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs | ||||||||||||||||||||||||
Release Data : | 2011-03-16 | ||||||||||||||||||||||||
Compound : |
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Authors : | Young, R.J., Adams, C., Blows, M., Brown, D., Burns-Kurtis, C.L., Chaudry, L., Chan, C., Convery, M.A., Davies, D.E., Exall, A.M., Foster, G., Harling, J.D., Hortense, E., Irving, W.R., Irvine, S., Jackson, S., Kleanthous, S., Pateman, A.J., Patikis, A.N., Roethka, T.J., Senger, S., Stelman, G.J., Toomey, J.R., West, R.I., Whittaker, C., Zhou, P., Watson, N.S. | ||||||||||||||||||||||||
Keywords : | BLOOD CLOTTING, HYDROLASE, SERINE PROTEASE, BLOOD COAGULATION | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.84 Å ) | ||||||||||||||||||||||||
Citation : |
Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Aminoindane and Phenylpyrrolidine P4 Motifs.
Young, R.J.,Adams, C.,Blows, M.
et al.
PubMed: 21349710 |
Reaction
Chain : | B | ||||||||
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UniProt : | P00742 (FA10_HUMAN) | ||||||||
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