Het-PDB Navi2 (PDB: 2XR6)

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Ligands
Code	Name	Link
07B	Dimethyl (1s,2s,4s,5s)-4,5-dihydroxycyclohexane-1,2-dicarboxylate	PoSSuM
AE9	2-azidoethanol	PoSSuM
CA	Calcium ion	PoSSuM
CL	Chloride ion	PoSSuM
MAN	Alpha-D-mannopyranose	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 2XR6

Code :

2XR6 PDBj RCSB PDB PDBe

Header :

SUGAR BINDING PROTEIN

Title :

Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo trimannoside mimic.

Release Data :

2011-10-19

Compound :

mol_id	molecule	chains	synonym
1	CD209 ANTIGEN	A	DC-SIGN, DENDRITIC CELL-SPECIFIC ICAM-3-GRABBING NON-INTEGRIN 1, DC-SIGN1, C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER L, CD209
	fragment: CARBOHYDRATE RECOGNITION DOMAIN, RESIDUES 250-404 mutation: YES

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PASK-IBA7PLUS

Authors :

Thepaut, M., Suitkeviciute, I., Sattin, S., Reina, J., Bernardi, A., Fieschi, F.

Keywords :

SUGAR BINDING PROTEIN, CARBOHYDRATE BINDING, MANNOSE

Exp. method :

X-RAY DIFFRACTION ( 1.35 Å )

Citation :

Unique Dc-Sign Clustering Activity of a Small Glycomimetic: A Lesson for Ligand Design.

Sutkeviciute, I.,Thepaut, M.,Sattin, S. et al.
(2014) Acs Chem.Biol. 9 : 1377

PDB ID: 2XR6