Brand  (β version)

PDB ID: 2W67

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
F34 N-[(3s,4r,5r,6r)-4,5,6-trihydroxyazepan-3-yl]acetamide PoSSuM
GOL Glycerol PoSSuM
CA Calcium ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 2W67   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : BtGH84 in complex with FMA34
Release Data : 2009-04-14
Compound :
mol_id molecule chains synonym
1 O-GLCNACASE BT_4395 A,B BTGH84, BETA-HEXOSAMINIDASE, N-ACETYL-BETA-GLUCOSAMINIDASE, BETA-N-ACETYLHEXOSAMINIDASE, HEXOSAMINIDASE B, GH84
ec: 3.2.1.52
Source :
mol_id organism_scientific expression_system
1 BACTEROIDES THETAIOTAOMICRON VPI-5482  (taxid:226186) ESCHERICHIA COLI  (taxid:511693)
atcc: 29148
expression_system_strain: BL21
expression_system_plasmid: YSBLLICPET28
Authors : He, Y., Davies, G.J.
Keywords : GLYCOSIDE HYDROLASE, COMPLEX, HYDROLASE, INHIBITOR, GLYCOSIDASE
Exp. method : X-RAY DIFFRACTION ( 2.25 Å )
Citation :

Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion.

Marcelo, F.,He, Y.,Yuzwa, S.A.  et al.
(2009)  J.Am.Chem.Soc.  131 : 5390

PubMed: 19331390
DOI: 10.1021/JA809776R

Reaction

Chain : A, B
UniProt : Q89ZI2 (OGA_BACTN)
Reaction: EC: Evidence:
Physiological Direction:
3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + N-acetyl-D-glucosamine 3.2.1.169 PubMed:16565725
-
3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H2O = L-threonyl-[protein] + N-acetyl-D-glucosamine 3.2.1.169 PubMed:16565725
-