PDB ID: 2UZO
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Structure summary
Code : | 2UZO PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | ||||||||||||
Release Data : | 2007-06-26 | ||||||||||||
Compound : |
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Source : |
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Authors : | Richardson, C.M., Dokurno, P., Murray, J.B., Surgenor, A.E. | ||||||||||||
Keywords : | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.30 Å ) | ||||||||||||
Citation : |
Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping.
Richardson, C.M.,Nunns, C.L.,Williamson, D.S.
et al.
PubMed: 17570665 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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