PDB ID: 2RGP
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 2RGP PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | TRANSFERASE | ||||||||||||
Title : | Structure of EGFR in complex with hydrazone, a potent dual inhibitor | ||||||||||||
Release Data : | 2008-08-26 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Abad, M.C. | ||||||||||||
Keywords : | Kinase domain, Alternative splicing, Anti-oncogene, ATP-binding, Cell cycle, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Receptor, Secreted, Transferase, Transmembrane, Tyrosine-protein kinase, Ubl conjugation | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.000 Å ) | ||||||||||||
Citation : |
4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors.
Xu, G.,Abad, M.C.,Connolly, P.J.
et al.
PubMed: 18653333 |
Reaction
Chain : | A | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P00533 (EGFR_HUMAN) | ||||||||
|