PDB ID: 2RA0
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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JNJ | 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]-1h-imidazol-1-yl}-2-fluorophenyl)-7-fluoro-1h-indazole-3-carboxamide | PoSSuM |
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Download interaction data: 2RA0
Structure summary
Code : | 2RA0 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | HYDROLASE | ||||||||||||||||||||||||
Title : | X-ray Structure of FXa in complex with 7-fluoroindazole | ||||||||||||||||||||||||
Release Data : | 2008-01-29 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Abad, M.C. | ||||||||||||||||||||||||
Keywords : | serine protease, Blood coagulation, Calcium, Cleavage on pair of basic residues, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Hydroxylation, Polymorphism, Zymogen | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.30 Å ) | ||||||||||||||||||||||||
Citation : |
7-fluoroindazoles as potent and selective inhibitors of factor xa.
Lee, Y.K.,Parks, D.J.,Lu, T.
et al.
PubMed: 18159923 |
Reaction
Chain : | L | ||||||||
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UniProt : | P00742 (FA10_HUMAN) | ||||||||
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