PDB ID: 2R3Q
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Structure summary
Code : | 2R3Q PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor | ||||||||||||
Release Data : | 2008-01-22 | ||||||||||||
Compound : |
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Source : |
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Authors : | Fischmann, T.O., Hruza, A.W., Madison, V.M., Duca, J.S. | ||||||||||||
Keywords : | SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, INHIBITION, CYCLIN-DEPENDENT KINASE, CANCER, ATP-binding, Cell division, Mitosis, Nucleotide-binding, Phosphorylation, Polymorphism, Transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.35 Å ) | ||||||||||||
Citation : |
Structure-guided discovery of cyclin-dependent kinase inhibitors.
Fischmann, T.O.,Hruza, A.,Duca, J.S.
et al.
PubMed: 17937404 Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors.
Dwyer, M.P.,Paruch, K.,Alvarez, C.
et al.
PubMed: 17904366 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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