Brand  (β version)

PDB ID: 2PFR

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Ligands
Code Name Style Show Link
SO4 Sulfate ion PoSSuM
COA Coenzyme a PoSSuM
UNX Unknown atom or ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 2PFR   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Human N-acetyltransferase 2
Release Data : 2007-05-15
Compound :
mol_id molecule chains synonym
1 Arylamine N-acetyltransferase 2 A,B Arylamide acetylase 2, Polymorphic arylamine N-acetyltransferase, PNAT, N- acetyltransferase type 2, NAT-2
ec: 2.3.1.5
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: NAT2, AAC2
expression_system_strain: BL21(DE3) codon plus RIL
expression_system_plasmid: pET28a-MHL
Authors : Tempel, W., Wu, H., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Grant, D.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Keywords : Arylamine N-acetyltransferase 2, Arylamide acetylase 2, structural genomics consortium, SGC, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.920 Å )
Citation :

The Crystal Structure of Human N-acetyltransferase 2 in complex with CoA

Wu, H.,Tempel, W.,Dombrovski, L.  et al.
to be published 

Reaction

Chain : A, B
UniProt : P11245 (ARY2_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
acetyl-CoA + an arylamine = an N-acetylarylamine + CoA 2.3.1.5 -
-