PDB ID: 2OZ7
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Structure summary
Code : | 2OZ7 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HORMONE RECEPTOR | ||||||||||||
Title : | Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with cyproterone acetate | ||||||||||||
Release Data : | 2007-03-27 | ||||||||||||
Compound : |
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Authors : | Bohl, C.E., Wu, Z., Miller, D.D., Bell, C.E., Dalton, J.T. | ||||||||||||
Keywords : | androgen receptor, anti-androgen, prostate cancer, HORMONE RECEPTOR | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design.
Bohl, C.E.,Wu, Z.,Miller, D.D.
et al.
PubMed: 17311914 |
Reaction
Chain : | A |
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UniProt : | P10275 (ANDR_HUMAN) |
Reaction : | - |