Brand  (β version)

PDB ID: 2OL4

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Ligands
Code Name Style Show Link
JPN 2-(2,4-dichlorophenoxy)-5-(3-phenylpropyl)phenol PoSSuM
NAD Nicotinamide-adenine-dinucleotide PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 2OL4   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of plasmodium falciparum enoyl ACP reductase with triclosan reductase
Release Data : 2007-07-17
Compound :
mol_id molecule chains synonym
1 Enoyl-acyl carrier reductase A,B Enoyl-ACP reductase
ec: 1.3.1.9
Source :
mol_id organism_scientific organism_common expression_system
1 Plasmodium falciparum  (taxid:5833) Malaria parasite P. falciparum Escherichia coli  (taxid:562)
gene: FabI
expression_system_strain: BL21(DE3) codon+-RIL cells
expression_system_vector_type: plasmid
expression_system_plasmid: pET28a
Authors : Tsai, H.
Keywords : PfENR, malaria, triclosan analog, Oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 2.26 Å )
Citation :

X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy

Freundlich, J.S.,Wang, F.,Tsai, H.-C.  et al.
(2007)  J.Biol.Chem.  282 : 25436 - 25444

PubMed: 17567585
DOI: 10.1074/jbc.M701813200

Reaction

Chain : A, B
UniProt : Q9BH77 (Q9BH77_PLAFA)
Reaction : -