Het-PDB Navi2 (PDB: 2KP4)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
A5L	9-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-9h-purin-6-amine
CFL	4-amino-1-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)pyrimidin-2(1h)-one
GFL	2-amino-9-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-1,9-dihydro-6h-purin-6-one
TAF	2'-deoxy-2'-fluoro-arabino-furanosyl thymine-5'-phosphate

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 2KP4

Code :

2KP4 PDBj RCSB PDB PDBe

Header :

DNA/RNA

Title :

Structure of 2'F-ANA/RNA hybrid duplex

Release Data :

2010-02-09

Compound :

mol_id	molecule	chains
1	DNA (5'-D((GFL)P(CFL)P(TAF)P(A5L)P(TAF)P(A5L)P(A5L)P(TAF)P(GFL)P(GFL))-3')	A

mol_id	molecule	chains
2	RNA (5'-R(CPCPAPUPUPAPUPAPGPC)-3')	B

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Gonzalez, C., Martin-Pintado, N., Watts, J., Gomez-Pinto, I., Dhama, M., Orozco, M., Schwartzentruber, J., Portella, G.

Keywords :

2-deoxy-2-fluoro-D-arabinose, FANA, nucleic acid structure, NMR/MD/TI, hybrid duplex, DNA-RNA complex

Exp. method :

SOLUTION NMR

Citation :

Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility.

Watts, J.K.,Martin-Pintado, N.,Gomez-Pinto, I. et al.
(2010) Nucleic Acids Res. 38 : 2498 - 2511

PubMed: 20071751
DOI: 10.1093/nar/gkp1225

PDB ID: 2KP4

Hetero Atom Contents

Structure summary