Het-PDB Navi2 (PDB: 2KO7)

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Ligands
Code	Name		Style	Show	Link
JZF	Ethyl (4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-dioxopiperidin-1-yl)acetate				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 2KO7

Code :

2KO7 PDBj RCSB PDB PDBe

Header :

ISOMERASE

Title :

Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with Cycloheximide-N-ethylethanoate

Release Data :

2009-09-29

Compound :

mol_id	molecule	chains
1	Peptidyl-prolyl cis-trans isomerase	A
	ec: 5.2.1.8

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Burkholderia pseudomallei (taxid:28450)	Pseudomonas pseudomallei	Escherichia coli (taxid:562)
	gene: fbp, BPSS1823 expression_system_vector: RIL

Authors :

Zheng, S., Leeper, T., Varani, G., Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Keywords :

cis-trans isomerase, FKBP, Cycloheximide-N-ethylethanoate, complex, Isomerase, Rotamase, Structural Genomics, SSGCID, Seattle Structural Genomics Center for Infectious Disease

Exp. method :

SOLUTION NMR

Citation :

The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.

Norville, I.H.,O'Shea, K.,Sarkar-Tyson, M. et al.
(2011) Biochem.J. 437 : 413 - 422

PubMed: 21574961
DOI: 10.1042/BJ20110345

Chain :

UniProt :

Q63J95 (Q63J95_BURPS)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
[protein]-peptidylproline (omega=180) = [protein]- peptidylproline (omega=0)	5.2.1.8	ARBA:ARBA00000971, PROSITE-ProRule:PRU00277, RuleBase:RU003915
	-

PDB ID: 2KO7

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Structure summary

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