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Ligands
Code Name Style Show Link
CA Calcium ion
SO4 Sulfate ion
FUC Alpha-L-fucopyranose
MFU Methyl alpha-L-fucopyranoside
Non-standard Residues
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Glycosylation
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Code : 2JDM   PDBj   RCSB PDB   PDBe
Header : LECTIN
Title : Mutant (S22A) of Pseudomonas aeruginosa lectin II (PA-IIL) complexed with methyl-a-L-fucopyranoside
Release Data : 2007-06-12
Compound :
mol_id molecule chains synonym
1 FUCOSE-BINDING LECTIN PA-IIL A,B,C,D PA-IIL
mutation: YES
Source :
mol_id organism_scientific expression_system
1 PSEUDOMONAS AERUGINOSA  (taxid:287) ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector: PET25PA2L
Authors : Adam, J., Pokorna, M., Sabin, C., Mitchell, E.P., Imberty, A., Wimmerova, M.
Keywords : ECTIN, GLYCOMIMETIC, CYSTIC FIBROSIS, LECTIN
Exp. method : X-RAY DIFFRACTION ( 1.70 Å )
Citation :

Engineering of Pa-Iil Lectin from Pseudomonas Aeruginosa - Unravelling the Role of the Specificity Loop for Sugar Preference.

Adam, J.,Pokorna, M.,Sabin, C.  et al.
(2007)  Bmc Struct.Biol.  7 : 36

PubMed: 17540045
DOI: 10.1186/1472-6807-7-36

Structural Basis for Oligosaccharide-Mediated Adhesion of Pseudomonas Aeruginosa in the Lungs of Cystic Fibrosis Patients

Mitchell, E.,Houles, C.,Sudakevitz, D.  et al.
(2002)  Nat.Struct.Biol.  9 : 918

PubMed: 12415289
DOI: 10.1038/NSB865

Binding of Different Monosaccharides by Lectin Pa-Iil from Pseudomonas Aeruginosa: Thermodynamics Data Correlated with X-Ray Structures.

Sabin, C.,Mitchell, E.,Pokorna, M.  et al.
(2006)  FEBS Lett.  580 : 982

PubMed: 16438968
DOI: 10.1016/J.FEBSLET.2006.01.030

Unusual Entropy-Driven Affinity of Chromobacterium Violaceum Lectin Cv-Iil Toward Fucose and Mannose.

Pokorna, M.,Cioci, G.,Perret, S.  et al.
(2006)  Biochemistry  45 : 7501

PubMed: 16768446
DOI: 10.1021/BI060214E

A New Ralstonia Solanacearum High-Affinity Mannose- Binding Lectin Rs-Iil Structurally Resembling the Pseudomonas Aeruginosa Fucose-Specific Lectin Pa- Iil

Sudakevitz, D.,Kostlanova, N.,Blatmanjan, G.  et al.
(2004)  Mol.Microbiol.  52 : 691

PubMed: 15101976
DOI: 10.1111/J.1365-2958.2004.04020.X

Chain : A, B, C, D
UniProt : Q9HYN5 (Q9HYN5_PSEAE)
Reaction : -