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Ligands
Code Name Style Show Link
DRY [(1-{3-[(6-benzoyl-1-propyl-2-naphthyl)oxy]propyl}-1h-indol-5-yl)oxy]acetic acid
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Code : 2HWQ   PDBj   RCSB PDB   PDBe
Header : LIGAND BINDING PROTEIN
Title : Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists
Release Data : 2007-08-07
Compound :
mol_id molecule chains synonym
1 Peroxisome proliferator-activated receptor gamma A,B PPAR-gamma
fragment: Ligand binding domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pGEX6P-1
Authors : Peng, Y.H., Lu, I.L., Mahindroo, N., Lin, C.H., Hsieh, H.P., Wu, S.Y.
Keywords : PPAR, LIGAND BINDING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.97 Å )
Citation :

Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists

Mahindroo, N.,Peng, Y.H.,Lin, C.H.  et al.
(2006)  J.Med.Chem.  49 : 6421 - 6424

PubMed: 17034149
DOI: 10.1021/jm060663c

Chain : A, B
UniProt : P37231 (PPARG_HUMAN)
Reaction : -