Het-PDB Navi2 (PDB: 2GH6)

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Ligands
Code	Name	Link
ZN	Zinc ion	PoSSuM
K	Potassium ion	PoSSuM
CF3	9,9,9-trifluoro-8-oxo-N-phenylnonanamide	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 2GH6

Code :

2GH6 PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound

Release Data :

2007-03-20

Compound :

mol_id	molecule	chains	synonym
1	Histone deacetylase-like amidohydrolase	A,B,C,D	HDAC-like amidohydrolase; HDAH
	ec: 3.5.1.-

Source :

mol_id	organism_scientific	expression_system
1	Alcaligenaceae bacterium FB188 (taxid:242601)	Escherichia coli (taxid:562)
	strain: DSM 11172 gene: hdaH, hdaH1 expression_system_strain: M15 expression_system_vector_type: plasmid expression_system_plasmid: pQE other_details: source organism synonym Bordetella sp. (strain FB188)

Authors :

Nielsen, T.K., Hildmann, C., Riester, D., Wegener, D., Schwienhorst, A., Ficner, R.

Keywords :

Histone deacetylase, zinc-ion, trifluoromethyl ketone, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.203 Å )

Citation :

Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor.

Nielsen, T.K.,Hildmann, C.,Riester, D. et al.
(2007) Acta Crystallogr.,Sect.F 63 : 270 - 273

PDB ID: 2GH6