PDB ID: 2FDP
Hetero Atom Contents
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Structure summary
Code : | 2FDP PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor | ||||||||||||
Release Data : | 2006-01-24 | ||||||||||||
Compound : |
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Source : |
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Authors : | Yang, W., Lu, W., Lu, Y., Zhong, M., Sun, J., Thomas, A.E., Wilkinson, J.M., Fucini, R.V., Lam, M., Randal, M., Shi, X.P., Jacobs, J.W., McDowell, R.S., Gordon, E.M., Ballinger, M.D. | ||||||||||||
Keywords : | ASPARTYL PROTEASE, BACE, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.500 Å ) | ||||||||||||
Citation : |
Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1.
Yang, W.,Lu, W.,Lu, Y.
et al.
PubMed: 16451048 |
Reaction
Chain : | A, B, C | ||||||||
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UniProt : | P56817 (BACE1_HUMAN) | ||||||||
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