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Ligands
Code Name Style Show Link
ACT Acetate ion
NA Sodium ion
DPR D-proline
MPD (4s)-2-methyl-2,4-pentanediol
Non-standard Residues
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Glycosylation
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Code : 2EJ6   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from Thermus thermophilus with bound D-proline
Release Data : 2007-09-18
Compound :
mol_id molecule chains
1 1-pyrroline-5-carboxylate dehydrogenase A,B
ec: 1.5.1.12
Source :
mol_id organism_scientific expression_system
1 Thermus thermophilus  (taxid:300852) Escherichia coli BL21(DE3)  (taxid:469008)
strain: HB8
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: PET11A
Authors : Inagaki, E., Sakamoto, K., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Keywords : Enzyme-inhibitor complex, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.06 Å )
Citation :

Crystal structure analysis of delta1-pyrroline-5-carboxylate dehydrogenase in ternary complex with inhibitor and NAD

Inagaki, E.,Ohshima, N.,Sakamoto, K.  et al.
To be Published 

Chain : A, B
UniProt : Q5SI02 (Q5SI02_THET8)
Reaction: EC: Evidence:
Physiological Direction:
H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L- glutamate + NADH 1.2.1.88 ARBA:ARBA00001468
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