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Ligands
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C5A (1s,3s)-1-aminocyclopentane-1,3-dicarboxylic acid
Non-standard Residues
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Glycosylation
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NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
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Code : 2E4W   PDBj   RCSB PDB   PDBe
Header : SIGNALING PROTEIN
Title : Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3S-ACPD
Release Data : 2007-02-27
Compound :
mol_id molecule chains synonym
1 Metabotropic glutamate receptor 3 A,B mGluR3, group II metabotropic glutamate receptor subtype 3
fragment: Extracellular region
mutation: N414Q, N439Q
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Trichoplusia ni  (taxid:7111)
expression_system_common: Cabbage looper
expression_system_cell_line: HIGH FIVE
expression_system_vector_type: BACULOVIRUS
Authors : Muto, T., Tsuchiya, D., Morikawa, K., Jingami, H.
Keywords : G-PROTEIN-COUPLED RECEPTOR, NEURON, CENTRAL NERVE SYSTEM, SIGNALING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors

Muto, T.,Tsuchiya, D.,Morikawa, K.  et al.
(2007)  Proc.Natl.Acad.Sci.Usa  104 : 3759 - 3764

PubMed: 17360426
DOI: 10.1073/pnas.0611577104

Chain : A, B
UniProt : P31422 (GRM3_RAT)
Reaction : -