PDB ID: 2C8Y
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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C3M | N-[(2r,3s)-3-amino-2-hydroxy-4-phenylbutyl]naphthalene-2-sulfonamide | PoSSuM | |||
DMS | Dimethyl sulfoxide | PoSSuM | |||
NA | Sodium ion | PoSSuM |
Code | Name | Show |
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TYS | O-sulfo-L-tyrosine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 2C8Y
Structure summary
Code : | 2C8Y PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||||||||||||||||||
Title : | thrombin inhibitors | ||||||||||||||||||||||||||||||||||||
Release Data : | 2006-07-04 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Howard, N., Abell, C., Blakemore, W., Carr, R., Chessari, G., Congreve, M., Howard, S., Jhoti, H., Murray, C.W., Seavers, L.C.A., van Montfort, R.L.M. | ||||||||||||||||||||||||||||||||||||
Keywords : | PROTEASE, BLOOD COAGULATION, THROMBIN, ACUTE PHASE, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, KRINGLE, PLASMA, SERINE PROTEASE, ZYMOGEN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.20 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors
Howard, N.,Abell, C.,Blakemore, W.
et al.
PubMed: 16480269 |
Reaction
Chain : | B | ||||||||
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UniProt : | P00734 (THRB_HUMAN) | ||||||||
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Chain : | I |
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UniProt : | P09945 (HIRV2_HIRME) |
Reaction : | - |