Het-PDB Navi2 (PDB: 2B9A)

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Ligands
Code	Name		Style	Show	Link
FBC	3',5'-difluorobiphenyl-4-carboxylic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 2B9A

Code :

2B9A PDBj RCSB PDB PDBe

Header :

HORMONE/GROWTH FACTOR

Title :

Human transthyretin (TTR) complexed with diflunisal analogues- TTR.3',5'-difluorobiphenyl-4-carboxylic acid

Release Data :

2005-10-25

Compound :

mol_id	molecule	chains	synonym
1	Transthyretin	A,B	Prealbumin, TBPA, TTR, ATTR

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	expression_system_vector_type: PLASMID expression_system_plasmid: PHNTR, PKNTR

Authors :

Palaninathan, S.K., Kelly, J.W., Sacchettini, J.C.

Keywords :

TTR, AMYLOID, TRANSTHYRETIN, HORMONE-GROWTH FACTOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 1.54 Å )

Citation :

Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis.

Adamski-Werner, S.L.,Palaninathan, S.K.,Sacchettini, J.C. et al.
(2004) J.Med.Chem. 47 : 355 - 374

PDB ID: 2B9A