PDB ID: 2A7Q
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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ADP | Adenosine-5'-diphosphate | PoSSuM | |||
CFB | 2-chloro-9-(2-deoxy-2-fluoro-B -D-arabinofuranosyl)-9h-purin-6-amine | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 2A7Q
Structure summary
Code : | 2A7Q PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of human dCK complexed with clofarabine and ADP | ||||||||||||
Release Data : | 2006-01-24 | ||||||||||||
Compound : |
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Authors : | Zhang, Y., Secrist III, J.A., Ealick, S.E. | ||||||||||||
Keywords : | alpha/beta parallel beta-sheet of 5 strands, transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.55 Å ) | ||||||||||||
Citation : |
The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation.
Zhang, Y.,Secrist, J.A.,Ealick, S.E.
PubMed: 16421443 |
Reaction
Chain : | A | ||||||||||||||||
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UniProt : | P27707 (DCK_HUMAN) | ||||||||||||||||
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