PDB ID: 2ZQA
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Structure summary
Code : | 2ZQA PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant | ||||||||||||
Release Data : | 2009-07-28 | ||||||||||||
Compound : |
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Source : |
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Authors : | Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M. | ||||||||||||
Keywords : | EXTENDED-SPECTRUM, ESBL, BETA-LACTAMASE, ACYL-ENZYME, COMPLEX, CEFOTAXIME, TOHO-1, HYDROLASE, Antibiotic resistance | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 0.95 Å ) | ||||||||||||
Citation : |
Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
Nitanai, Y.,Shimamura, T.,Uchiyama, T.
et al.
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Reaction
Chain : | A | ||||||||
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UniProt : | Q47066 (BLT1_ECOLX) | ||||||||
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