Brand  (β version)

PDB ID: 2YME

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Ligands
Code Name Style Show Link
CWB 1-methyl-N-[(1r,5s)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide PoSSuM
PO4 Phosphate ion PoSSuM
NA Sodium ion PoSSuM
Non-standard Residues
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Glycosylation
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NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 2YME   PDBj   RCSB PDB   PDBe
Header : RECEPTOR
Title : Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with granisetron
Release Data : 2012-12-26
Compound :
mol_id molecule chains synonym
1 SOLUBLE ACETYLCHOLINE RECEPTOR A,B,C,D,E,F,G,H,I,J ACHBP
fragment: ACETYLCHOLINE BINDING DOMAIN, RESIDUES 20-224
mutation: YES
Source :
mol_id organism_scientific organism_common expression_system
1 APLYSIA CALIFORNICA  (taxid:6500) CALIFORNIA SEA HARE SPODOPTERA FRUGIPERDA  (taxid:7108)
expression_system_common: FALL ARMYWORM
expression_system_strain: SF21
expression_system_vector_type: PLASMID
expression_system_vector: PFASTBAC
Authors : Kesters, D., Thompson, A.J., Brams, M., Elk, R.v., Spurny, R., Geitmann, M., Villalgordo, J.M., Guskov, A., Danielson, U.H., Lummis, S.C.R., Smit, A.B., Ulens, C.
Keywords : RECEPTOR, PENTAMERIC LIGAND-GATED ION CHANNEL
Exp. method : X-RAY DIFFRACTION ( 2.40 Å )
Citation :

Structural Basis of Ligand Recognition in 5-Ht3 Receptors.

Kesters, D.,Thompson, A.J.,Brams, M.  et al.
(2013)  Embo Rep.  14 : 49

PubMed: 23196367
DOI: 10.1038/EMBOR.2012.189

Reaction

Chain : A, B, C, D, E, F, G, H, I, J
UniProt : Q8WSF8 (Q8WSF8_APLCA)
Reaction : -