Brand  (β version)

PDB ID: 2YLP

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Ligands
Code Name Style Show Link
056 3-[(2,4-dichlorophenyl)methylsulfanylmethyl]benzoic acid PoSSuM
SO4 Sulfate ion PoSSuM
TES Testosterone PoSSuM
Non-standard Residues
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Structure summary

Code : 2YLP   PDBj   RCSB PDB   PDBe
Header : HORMONE RECEPTOR
Title : TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING
Release Data : 2011-07-06
Compound :
mol_id molecule chains synonym
1 ANDROGEN RECEPTOR A DIHYDROTESTOSTERONE RECEPTOR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 4
fragment: LIGAND-BINDING DOMAIN, RESIDUES 664-919
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_vector: PGEX
Authors : Lack, N.A., Axerio, P., Tavassoli, P., Kuchenbecker, K., Han, F.Q., Chan, K.H., Feau, C., LeBlanc, E., Tomlinson, E., Guy, R.K., Rennie, P.S., Cherkasov, A.
Keywords : HORMONE RECEPTOR, BINDING FUNCTION 3
Exp. method : X-RAY DIFFRACTION ( 2.30 Å )
Citation :

Targeting the Binding Function 3 (Bf3) Site of the Human Androgen Receptor Through Virtual Screening.

Lack, N.A.,Axerio-Cilies, P.,Tavassoli, P.  et al.
(2011)  J.Med.Chem.  54 : 8563

PubMed: 22047606
DOI: 10.1021/JM201098N

Reaction

Chain : A
UniProt : P10275 (ANDR_HUMAN)
Reaction : -