Het-PDB Navi2 (PDB: 2YJ1)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
B3A	(3s)-3-aminobutanoic acid
B3D	3-aminopentanedioic acid
B3E	(3s)-3-aminohexanedioic acid
B3Q	(3s)-3,6-diamino-6-oxohexanoic acid
HR7	(3s)-3-amino-6-[(diaminomethylidene)amino]hexanoic acid
HT7	(3s)-3-amino-4-(1h-indol-3-yl)butanoic acid

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
ACE	Acetyl group
NH2	Amino group

Download interaction data: 2YJ1

Code :

2YJ1 PDBj RCSB PDB PDBe

Header :

APOPTOSIS

Title :

Puma BH3 foldamer in complex with Bcl-xL

Release Data :

2011-10-12

Compound :

mol_id	molecule	chains	synonym
1	BCL-2-LIKE PROTEIN 1	A,C	BCL2-L-1, APOPTOSIS REGULATOR BCL-X BCL-XL
	fragment: RESIDUES 1-26,83-209

mol_id	molecule	chains
2	ALPHA-BETA-PUMA BH3 FOLDAMER	B,D

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_vector: PGEX

mol_id	organism_scientific
2	SYNTHETIC CONSTRUCT (taxid:32630)
	synthetic: yes

Authors :

Lee, E.F., Smith, B.J., Horne, W.S., Mayer, K.N., Evangelista, M., Colman, P.M., Gellman, S.H., Fairlie, W.D.

Keywords :

APOPTOSIS, MEMBRANE PROTEIN, FOLDAMER, BH3 DOMAIN, AUTOPHAGY

Exp. method :

X-RAY DIFFRACTION ( 2.24 Å )

Citation :

Structural Basis of Bcl-Xl Recognition by a Bh3-Mimetic Alpha-Beta-Peptide Generated Via Sequence-Based Design

Lee, E.F.,Smith, B.J.,Horne, W.S. et al.
(2011) Chembiochem 12 : 2025

PDB ID: 2YJ1