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Ligands
Code Name Style Show Link
9TN Debutanoyl thapsigargin
K Potassium ion
MG Magnesium ion
Non-standard Residues
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Code : 2YFY   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : SERCA in the HnE2 State Complexed With Debutanoyl Thapsigargin
Release Data : 2011-06-29
Compound :
mol_id molecule chains synonym
1 SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 A SERCA1, SR CA(2+)-ATPASE 1, CALCIUM PUMP 1, CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC RETICULUM TYPE\,FAST TWITCH SKELETAL MUSCLE ISOFORM, ENDOPLASMIC RETICULUM CLASS 1/2 CA(2+) ATPASE
ec: 3.6.3.8
fragment: RESIDUES 1-994
Source :
mol_id organism_scientific organism_common
1 ORYCTOLAGUS CUNICULUS  (taxid:9986) RABBIT
tissue: FAST TWITCH SKELETAL MUSCLE
Authors : Sonntag, Y., Musgaard, M., Olesen, C., Schiott, B., Moller, J.V., Nissen, P., Thogersen, L.
Keywords : MEMBRANE PROTEIN, SERCA, P-TYPE ATPASE, PROSTATE CANCER, HYDROLASE, ION TRANSPORT
Exp. method : X-RAY DIFFRACTION ( 3.10 Å )
Citation :

Mutual Adaptation of a Membrane Protein and its Lipid Bilayer During Conformational Changes.

Sonntag, Y.,Musgaard, M.,Olesen, C.  et al.
(2011)  Nat.Commun.  2 : 304

PubMed: 21556058
DOI: 10.1038/NCOMMS1307

Chain : A
UniProt : P04191 (AT2A1_RABIT)
Reaction: EC: Evidence:
Physiological Direction:
ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate 7.2.2.10 PubMed:10914677, PubMed:11438520, PubMed:15189864, PubMed:18075584, PubMed:23996003, PubMed:29081402, PubMed:8117720
left-to-right PubMed:10914677