Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
EU Europium ion
EEU Estradiol-pyridinium tetraacetic acid
FMT Formic acid
Code : 2YAT
Header : TRANSCRIPTION
Title : Crystal structure of estradiol derived metal chelate and estrogen receptor-ligand binding domain complex
Release Data : 2011-06-01
Compound :
mol_id molecule chains synonym
1 ESTROGEN RECEPTOR A ESTROGEN RECEPTOR ALPHA, ER, ER-ALPHA, ESTRADIOL RECEPTOR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP A MEMBER 1
fragment: LIGAND-BINDING DOMAIN, RESIDUES 301-551
mutation: YES
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_vector: PET21B
Authors : Li, M.J., Greenblatt, H.M., Dym, O., Albeck, S., Degani, H., Sussman, J.L.
Keywords : TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 2.602 Å )
Citation :

Structure of Estradiol Metal Chelate and Estrogen Receptor Complex: The Basis for Designing a New Class of Selective Estrogen Receptor Modulators.

Li, M.J.,Greenblatt, H.M.,Dym, O.  et al.
(2011)  J.Med.Chem.  54 : 3575

PubMed: 21473635
DOI: 10.1021/JM200192Y

Chain : A
UniProt : P03372 (ESR1_HUMAN)
Reaction : -