PDB ID: 2Y1G
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Structure summary
Code : | 2Y1G PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | X-ray structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with a 3,4- dichlorophenyl-substituted FR900098 analogue and manganese. | ||||||||||||
Release Data : | 2011-06-29 | ||||||||||||
Compound : |
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Source : |
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Authors : | Henriksson, L.M., Larsson, A.M.S., Bergfors, T., Bjorkelid, C., Unge, T., Mowbray, S.L., Jones, T.A. | ||||||||||||
Keywords : | OXIDOREDUCTASE, DOXP/MEP PATHWAY | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.95 Å ) | ||||||||||||
Citation : |
Design, Synthesis and X-Ray Crystallographic Studies of Alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
Andaloussi, M.,Henriksson, L.M.,Wieckowska, A.
et al.
PubMed: 21678907 The 1.9 A Resolution Structure of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, a Potential Drug Target.
Henriksson, L.M.,Bjorkelid, C.,Mowbray, S.L.
et al.
PubMed: 16790937 Structures of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Provide New Insights Into Catalysis.
Henriksson, L.M.,Unge, T.,Carlsson, J.
et al.
PubMed: 17491006 |
Reaction
Chain : | A, B |
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UniProt : | A2VLK3 |
Reaction : | - |