Het-PDB Navi2 (PDB: 2XN5)

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Ligands
Code	Name	Link
CA	Calcium ion	PoSSuM
EDO	1,2-ethanediol	PoSSuM
FUN	5-(aminosulfonyl)-4-chloro-2-[(2-furylmethyl)amino]benzoic acid	PoSSuM

Non-standard Residues
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Download interaction data: 2XN5

Code :

2XN5 PDBj RCSB PDB PDBe

Header :

TRANSPORT

Title :

Crystal structure of thyroxine-binding globulin complexed with Furosemide

Release Data :

2011-02-16

Compound :

mol_id	molecule	chains	synonym
1	THYROXINE-BINDING GLOBULIN	A	T4-BINDING GLOBULIN, SERPIN A7
	fragment: RESIDUES 32-380 mutation: YES other_details: RESIDUES 346-355 OF TBG WERE REPLACED BY GAMFLEAIPRS

mol_id	molecule	chains	synonym
2	THYROXINE-BINDING GLOBULIN	B	T4-BINDING GLOBULIN, SERPIN A7
	fragment: RESIDUES 381-415

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_vector: PSUMO3

mol_id	organism_scientific	organism_common	expression_system
2	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_vector: PSUMO3

Authors :

Qi, X., Yan, Y., Wei, Z., Zhou, A.

Keywords :

TRANSPORT, CLEAVED PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.70 Å )

Citation :

Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.

Qi, X.,Loiseau, F.,Chan, W.L. et al.
(2011) J.Biol.Chem. 286 : 16163

PDB ID: 2XN5