Brand  (β version)

PDB ID: 2XIK

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Ligands
Code Name Style Show Link
EDO 1,2-ethanediol PoSSuM
J60 5-[(E)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide PoSSuM
Non-standard Residues
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TPO Phosphothreonine
Glycosylation
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Structure summary

Code : 2XIK   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1)
Release Data : 2010-07-14
Compound :
mol_id molecule chains synonym
1 SERINE/THREONINE PROTEIN KINASE 25 A STERILE 20/OXIDANT STRESS-RESPONSE KINASE 1, STE20/OXIDANT STRESS RESPONSE KINASE 1, SOK-1, STE20-LIKE KINASE
ec: 2.7.11.1
fragment: RESIDUES 1-293
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN ESCHERICHIA COLI  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_variant: R3
expression_system_vector: PNIC-ZB
Authors : Muniz, J.R.C., Rellos, P., Ugochukwu, E., Vollmar, M., Allerston, C., Chaikuad, A., Savitsky, P., Berridge, G., Brenner, B., Elkins, J.M., Daga, N., Gileadi, O., Mahajan, P., Shrestha, B., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S.
Keywords : TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.97 Å )
Citation :

Structure of Human Ysk1 (Yeast Sps1-Ste20-Related Kinase 1)

Muniz, J.R.C.,Rellos, P.,Vollmar, M.  et al.
To be Published 

Reaction

Chain : A
UniProt : O00506 (STK25_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 -
-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 -
-