Brand  (β version)

PDB ID: 2XE4

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
GOL Glycerol PoSSuM
NA Sodium ion PoSSuM
PGO S-1,2-propanediol PoSSuM
PGR R-1,2-propanediol PoSSuM
PO4 Phosphate ion PoSSuM
Non-standard Residues
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FC0 N-carboxy-L-phenylalanine
RGL Arginal
Glycosylation
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Structure summary

Code : 2XE4   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/INHIBITOR
Title : Structure of Oligopeptidase B from Leishmania major
Release Data : 2010-10-06
Compound :
mol_id molecule chains synonym
1 OLIGOPEPTIDASE B A FAMILY S9A-LIKE PROTEIN, SERINE PEPTIDASE
ec: 3.4.21.83
mutation: YES
mol_id molecule chains
2 ANTIPAIN B
Source :
mol_id organism_scientific expression_system
1 LEISHMANIA MAJOR  (taxid:5664) ESCHERICHIA COLI  (taxid:469008)
strain: FRIEDLIN
expression_system_strain: BL21(DE3)(PLYS)
expression_system_vector: PET28A
expression_system_plasmid: PBP218
mol_id organism_scientific
2 ACTINOBACTERIA  (taxid:1760)
Authors : McLuskey, K., Paterson, N.G., Bland, N.D., Mottram, J.C., Isaacs, N.W.
Keywords : HYDROLASE-INHIBITOR COMPLEX, HYDROLASE, PROTEASE INHIBITOR TRYPANOSOMES, CLAN SC
Exp. method : X-RAY DIFFRACTION ( 1.650 Å )
Citation :

Crystal Structure of Leishmania Major Oligopeptidase B Gives Insight Into the Enzymatic Properties of a Trypanosomatid Virulence Factor.

Mcluskey, K.,Paterson, N.G.,Bland, N.D.  et al.
(2010)  J.Biol.Chem.  285 : 39249

PubMed: 20926390
DOI: 10.1074/JBC.M110.156679

Reaction

Chain : A
UniProt : Q4QHU7 (Q4QHU7_LEIMA)
Reaction : -