Brand  (β version)

PDB ID: 2WSB

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Ligands
Code Name Style Show Link
MG Magnesium ion PoSSuM
NAD Nicotinamide-adenine-dinucleotide PoSSuM
POL N-propanol PoSSuM
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Glycosylation
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Structure summary

Code : 2WSB   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of the short-chain dehydrogenase Galactitol- Dehydrogenase (GatDH) of Rhodobacter sphaeroides in complex with NAD
Release Data : 2010-04-28
Compound :
mol_id molecule chains
1 GALACTITOL DEHYDROGENASE A,B,C,D
ec: 1.1.1.16
Source :
mol_id organism_scientific expression_system
1 RHODOBACTER SPHAEROIDES  (taxid:1063) ESCHERICHIA COLI  (taxid:469008)
strain: D
atcc: 17023
expression_system_strain: BL21(DE3)
expression_system_plasmid: PET24
Authors : Carius, Y., Christian, H., Faust, A., Kornberger, P., Kohring, G.W., Giffhorn, F., Scheidig, A.J.
Keywords : OXIDOREDUCTASE, SDR, ROSSMANN FOLD, TAGATOSE
Exp. method : X-RAY DIFFRACTION ( 1.25 Å )
Citation :

Structural Insight Into Substrate Differentiation of the Sugar-Metabolizing Enzyme Galactitol Dehydrogenase from Rhodobacter Sphaeroides D.

Carius, Y.,Christian, H.,Faust, A.  et al.
(2010)  J.Biol.Chem.  285 : 20006

PubMed: 20410293
DOI: 10.1074/JBC.M110.113738

Reaction

Chain : A, B, C, D
UniProt : C0KTJ6 (GATDH_CERSP)
Reaction: EC: Evidence:
Physiological Direction:
galactitol + NAD(+) = H(+) + keto-L-tagatose + NADH 1.1.1.406 PubMed:7551050
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