PDB ID: 2WO9
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Structure summary
Code : | 2WO9 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | MMP12 complex with a beta hydroxy carboxylic acid | ||||||||||||
Release Data : | 2009-09-08 | ||||||||||||
Compound : |
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Source : |
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Authors : | Holmes, I.P., Gaines, S., Watson, S.P., Lorthioir, O., Walker, A., Baddeley, S.J., Herbert, S., Egan, D., Convery, M.A., Singh, O.M.P., Gross, J.W., Strelow, J.M., Smith, R.H., Amour, A.J., Brown, D., Martin, S.L. | ||||||||||||
Keywords : | HYDROLASE, POLYMORPHISM, GLYCOPROTEIN, METAL-BINDING, MATRIX METALLOPROTEASE MMP-12 COMPLEX STRUCTURE, METALLOPROTEASE, EXTRACELLULAR MATRIX, ZYMOGEN, PROTEASE, SECRETED | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.70 Å ) | ||||||||||||
Citation : |
The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors.
Holmes, I.P.,Gaines, S.,Watson, S.P.
et al.
PubMed: 19703773 |
Reaction
Chain : | A, B, C, D | ||||||||
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UniProt : | P39900 (MMP12_HUMAN) | ||||||||
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