PDB ID: 2W3L
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DRO | 1-(2-{[(3s)-3-(aminomethyl)-3,4-dihydroisoquinolin-2(1h)-yl]carbonyl}phenyl)-4-chloro-5-methyl-N,N-diphenyl-1h-pyrazole-3-carboxamide | PoSSuM |
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Download interaction data: 2W3L
Structure summary
Code : | 2W3L PDBj RCSB PDB PDBe | ||||||||||||
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Header : | APOPTOSIS | ||||||||||||
Title : | Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex | ||||||||||||
Release Data : | 2008-12-09 | ||||||||||||
Compound : |
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Authors : | Porter, J., Payne, A., de Candole, B., Ford, D., Hutchinson, B., Trevitt, G., Turner, J., Edwards, C., Watkins, C., Whitcombe, I., Davis, J., Stubberfield, C., Fisher, M., Lamers, M. | ||||||||||||
Keywords : | APOPTOSIS | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.10 Å ) | ||||||||||||
Citation : |
Tetrahydroisoquinoline Amide Substituted Phenyl Pyrazoles as Selective Bcl-2 Inhibitors.
Porter, J.,Payne, A.,De Candole, B.
et al.
PubMed: 19027294 |
Reaction
Chain : | A, B |
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UniProt : | P10415 (BCL2_HUMAN) |
Reaction : | - |