PDB ID: 2W05
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Structure summary
Code : | 2W05 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5b | ||||||||||||
Release Data : | 2008-10-14 | ||||||||||||
Compound : |
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Source : |
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Authors : | Anderson, M., Andrews, D.M., Barker, A.J., Brassington, C.A., Breed, J., Byth, K.F., Culshaw, J.D., Finlay, M.R., Fisher, E., Green, C.P., Heaton, D.W., Nash, I.A., Newcombe, N.J., Oakes, S.E., Pauptit, R.A., Roberts, A., Stanway, J.J., Thomas, A.P., Tucker, J.A., Weir, H.M. | ||||||||||||
Keywords : | KINASE, MITOSIS, CELL CYCLE, TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, POLYMORPHISM, CELL DIVISION, PHOSPHOPROTEIN, PHOSPHORYLATION, NUCLEOTIDE-BINDING | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.9 Å ) | ||||||||||||
Citation : |
Imidazoles: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors.
Anderson, M.,Andrews, D.M.,Barker, A.J.
et al.
PubMed: 18815031 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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