PDB ID: 2V11
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Structure summary
Code : | 2V11 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal Structure of Renin with Inhibitor 6 | ||||||||||||
Release Data : | 2007-07-03 | ||||||||||||
Compound : |
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Source : |
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Authors : | Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., Cohen, N.C., Stutz, S., Cumin, F., Fuhrer, W., Wood, J.M., Grutter, M.G. | ||||||||||||
Keywords : | GLYCOPROTEIN, INHIBITOR-COMPLEX, ASPARTYL PROTEASE, ZYMOGEN, PROTEASE, HYDROLASE, POLYMORPHISM, ALTERNATIVE SPLICING, HYDROLASE(ACID PROTEINASE), CLEAVAGE ON PAIR OF BASIC RESIDUES | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.1 Å ) | ||||||||||||
Citation : |
Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Rahuel, J.,Rasetti, V.,Maibaum, J.
et al.
PubMed: 10903938 The Crystal Structures of Recombinant Glycosylated Human Renin Alone and in Complex with a Transition State Analog Inhibitor.
Rahuel, J.,Priestle, J.P.,Grutter, M.G.
PubMed: 1807356 |
Reaction
Chain : | C, O | ||||||||
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UniProt : | P00797 (RENI_HUMAN) | ||||||||
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