PDB ID: 2UZB
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 2UZB PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | TRANSFERASE | ||||||||||||||||||||||||
Title : | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | ||||||||||||||||||||||||
Release Data : | 2007-06-26 | ||||||||||||||||||||||||
Compound : |
|
||||||||||||||||||||||||
Source : |
|
||||||||||||||||||||||||
Authors : | Richardson, C.M., Dokurno, P., Murray, J.B., Surgenor, A.E. | ||||||||||||||||||||||||
Keywords : | TRANSFERASE, ATP-BINDING, PHOSPHORYLATION, CDK2, KINASE, CYCLIN, MITOSIS, CELL CYCLE, CELL DIVISION, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, THIAZOLIDINONE LIGAND | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.70 Å ) | ||||||||||||||||||||||||
Citation : |
Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping.
Richardson, C.M.,Nunns, C.L.,Williamson, D.S.
et al.
PubMed: 17570665 |
Reaction
Chain : | A, C | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
|
Chain : | B, D |
---|---|
UniProt : | P20248 (CCNA2_HUMAN) |
Reaction : | - |