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Ligands
Code Name Style Show Link
01G 8-morpholin-4-ylguanosine 5'-(tetrahydrogen triphosphate)
MG Magnesium ion
Non-standard Residues
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Glycosylation
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Code : 2R75   PDBj   RCSB PDB   PDBe
Header : CELL CYCLE
Title : Aquifex aeolicus FtsZ with 8-morpholino-GTP
Release Data : 2008-07-22
Compound :
mol_id molecule chains
1 Cell division protein ftsZ 1
Source :
mol_id organism_scientific expression_system
1 Aquifex aeolicus  (taxid:63363) Escherichia coli  (taxid:562)
strain: VF5
gene: ftsZ
expression_system_strain: BL21(AI)
expression_system_vector_type: plasmid
expression_system_plasmid: pHis17
other_details: Gene cloned into NdeI/HindIII restriction sites
Authors : Lappchen, T., Pinas, V.A., Hartog, A.F., Koomen, G.J., Schaffner-Barbero, C., Andreu, J.M., Trambaiolo, D., Lowe, J., Juhem, A., Popov, A.V., den Blaauwen, T.
Keywords : GTPase, tubulin-like, inhibitor, CELL CYCLE
Exp. method : X-RAY DIFFRACTION ( 1.402 Å )
Citation :

Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites

Lappchen, T.,Pinas, V.A.,Hartog, A.F.  et al.
(2008)  Chem.Biol.  15 : 189 - 199

PubMed: 18291323
DOI: 10.1016/j.chembiol.2007.12.013

Chain : 1
UniProt : O66809 (FTSZ_AQUAE)
Reaction : -