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Ligands
Code Name Style Show Link
SO4 Sulfate ion
Non-standard Residues
Code Name Show
DLY D-lysine
DAL D-alanine
DCY D-cysteine
DAS D-aspartic acid
DTY D-tyrosine
DPR D-proline
DGL D-glutamic acid
DTR D-tryptophan
DGN D-glutamine
DLE D-leucine
Glycosylation
Code Name Emphasize
Modification
Code Name Show
ACE Acetyl group
NH2 Amino group
Code : 2R5B   PDBj   RCSB PDB   PDBe
Header : VIRAL PROTEIN/inhibitor
Title : Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7
Release Data : 2007-10-02
Compound :
mol_id molecule chains
1 gp41 N-peptide A,B,C
mol_id molecule chains
2 HIV entry inhibitor PIE7 H,K,L
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
other_details: peptide synthesis
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
other_details: peptide synthesis
Authors : VanDemark, A.P., Welch, B., Heroux, A., Hill, C.P., Kay, M.S.
Keywords : HIV, viral entry, PIE, VIRAL PROTEIN-inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 2.000 Å )
Citation :

Potent D-peptide inhibitors of HIV-1 entry

Welch, B.D.,Vandemark, A.P.,Heroux, A.  et al.
(2007)  Proc.Natl.Acad.Sci.Usa  104 : 16828 - 16833

PubMed: 17942675
DOI: 10.1073/pnas.0708109104