Brand  (β version)

PDB ID: 2QTT

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Ligands
Code Name Style Show Link
ADE Adenine PoSSuM
EDO 1,2-ethanediol PoSSuM
FMC (1s)-1-(7-amino-1h-pyrazolo[4,3-D]pyrimidin-3-yl)-1,4-anhydro-D-ribitol PoSSuM
Non-standard Residues
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Structure summary

Code : 2QTT   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal Structure of Arabidopsis thaliana 5'-Methylthioadenosine nucleosidase in complex with Formycin A
Release Data : 2008-04-01
Compound :
mol_id molecule chains
1 5'-methylthioadenosine nucleosidase A,B
ec: 3.2.2.16
Source :
mol_id organism_scientific organism_common expression_system
1 Arabidopsis thaliana  (taxid:3702) Thale cress Escherichia coli  (taxid:562)
gene: AT4g38800
expression_system_strain: BL21 C+
expression_system_vector_type: plasmid
expression_system_plasmid: pET28a+
Authors : Siu, K.K.W., Howell, P.L.
Keywords : nucleosidase, apo, rossmann fold, hydrolase
Exp. method : X-RAY DIFFRACTION ( 1.93 Å )
Citation :

Molecular determinants of substrate specificity in plant 5'-methylthioadenosine nucleosidases.

Siu, K.K.,Lee, J.E.,Sufrin, J.R.  et al.
(2008)  J.Mol.Biol.  378 : 112 - 128

PubMed: 18342331
DOI: 10.1016/j.jmb.2008.01.088

Reaction

Chain : A, B
UniProt : Q9T0I8 (MTN1_ARATH)
Reaction: EC: Evidence:
Physiological Direction:
H2O + S-methyl-5'-thioadenosine = 5-(methylsulfanyl)-D-ribose + adenine 3.2.2.16 PubMed:18342331, PubMed:19249293
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