Brand  (β version)

PDB ID: 2QO3

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ACT Acetate ion PoSSuM
CER (2s, 3r)-3-hydroxy-4-oxo-7,10-trans,trans-dodecadienamide PoSSuM
CL Chloride ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 2QO3   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase
Release Data : 2007-09-04
Compound :
mol_id molecule chains synonym
1 EryAII Erythromycin polyketide synthase modules 3 and 4 A,B 6 Deoxyerythronolide B Synthase
ec: 2.3.1.94
fragment: ketosynthase-acyltransferase didomain of didomain module 3
Source :
mol_id organism_scientific expression_system
1 Saccharopolyspora erythraea  (taxid:1836) Escherichia coli BL21  (taxid:511693)
gene: eryAII
expression_system_strain: BL21
expression_system_vector_type: plasmid
expression_system_plasmid: PAYC09
Authors : Khosla, C., Cane, E.D., Tang, Y., Chen, Y.A., Kim, C.Y.
Keywords : ketosynthase, acyltransferase, Phosphopantetheine, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.59 Å )
Citation :

Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase

Tang, Y.,Chen, Y.A.,Kim, C.Y.  et al.
(2007)  Chem.Biol.  14 : 931 - 943

PubMed: 17719492
DOI: 10.1016/j.chembiol.2007.07.012

Structure-based dissociation of a type I polyketide synthase module

Chen, Y.A.,Cane, E.D.,Khosla, C.
(2007)  Chem.Biol.  14 : 784 - 792

PubMed: 17656315
DOI: 10.1016/j.chembiol.2007.05.015

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase

Tang, Y.,Kim, C.Y.,Mathews, I.I.  et al.
(2006)  Proc.Natl.Acad.Sci.Usa  103 : 11124 - 11129

PubMed: 16844787
DOI: 10.1073/pnas.0601924103

Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase

Kim, C.Y.,Alekseyev, V.Y.,Chen, Y.A.  et al.
(2004)  Biochemistry  43 : 13892 - 13898

PubMed: 15518537
DOI: 10.1021/bi048418n

Reaction

Chain : A, B
UniProt : A4F7P0 (A4F7P0_SACEN)
Reaction : -