Brand  (β version)

PDB ID: 2QKR

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Ligands
Code Name Style Show Link
IXM (z)-1h,1'H-[2,3']biindolylidene-3,2'-dione-3-oxime PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 2QKR   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound
Release Data : 2007-09-04
Compound :
mol_id molecule chains
1 Cdc2-like CDK2/CDC28 like protein kinase A
ec: 2.7.11.22
Source :
mol_id organism_scientific expression_system
1 Cryptosporidium parvum Iowa II  (taxid:353152) Escherichia coli  (taxid:562)
strain: Iowa type II
gene: cgd5_2510
expression_system_strain: DH5a
expression_system_vector_type: Plasmid
expression_system_plasmid: p15-mhl-LIC
Authors : Wernimont, A.K., Dong, A., Lew, J., Lin, Y.H., Hassanali, A., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J.D., Structural Genomics Consortium (SGC)
Keywords : Cp-specific cyclin-dependent kinase, malaria, cryptosporidium parvum, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.600 Å )
Citation :

Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound.

Wernimont, A.K.,Dong, A.,Lew, J.  et al.
To be Published 

Reaction

Chain : A
UniProt : Q5CRJ8 (Q5CRJ8_CRYPI)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.22 ARBA:ARBA00000584
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ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.22 ARBA:ARBA00000875
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[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho- [DNA-directed RNA polymerase] 2.7.11.23 ARBA:ARBA00000889
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