PDB ID: 2QK5
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Structure summary
Code : | 2QK5 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Structure of BACE1 bound to SCH626485 | ||||||||||||
Release Data : | 2008-03-11 | ||||||||||||
Compound : |
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Source : |
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Authors : | Strickland, C.O., Iserloh, U. | ||||||||||||
Keywords : | BACE1, protease, Alternative splicing, Aspartyl protease, Glycoprotein, Hydrolase, Membrane, Transmembrane, Zymogen | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.200 Å ) | ||||||||||||
Citation : |
Potent pyrrolidine- and piperidine-based BACE-1 inhibitors.
Iserloh, U.,Wu, Y.,Cumming, J.N.
et al.
PubMed: 18023580 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P56817 (BACE1_HUMAN) | ||||||||
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