Het-PDB Navi2 (PDB: 2QIR)

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Ligands
Code	Name		Style	Show	Link
9CS	(1r,2s,3s,4r,6s)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside				PoSSuM
COA	Coenzyme a				PoSSuM

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Download interaction data: 2QIR

Code :

2QIR PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A and kanamycin

Release Data :

2008-04-08

Compound :

mol_id	molecule	chains
1	Aminoglycoside 6-N-acetyltransferase type Ib11	A
	ec: 2.3.1.82 mutation: L106Q, S107L

Source :

mol_id	organism_scientific	expression_system
1	Salmonella typhimurium (taxid:602)	Escherichia coli (taxid:562)
	gene: aac(6')-Ib expression_system_vector_type: PLASMID expression_system_plasmid: pET101

Authors :

Maurice, F., Broutin, I., Podglajen, I., Benas, P., Collatz, E., Dardel, F.

Keywords :

Aminoglycoside resistance, acetyltransferase, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.400 Å )

Citation :

Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance.

Maurice, F.,Broutin, I.,Podglajen, I. et al.
(2008) Embo Rep. 9 : 344 - 349

PDB ID: 2QIR