Het-PDB Navi2 (PDB: 2QEI)

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Ligands
Code	Name	Link
NA	Sodium ion	PoSSuM
ALA	Alanine	PoSSuM
CXX	3-(3-chloro-5h-dibenzo[B,f]azepin-5-yl)-N,N-dimethylpropan-1-amine	PoSSuM
BOG	Octyl beta-D-glucopyranoside	PoSSuM

Non-standard Residues
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Download interaction data: 2QEI

Code :

2QEI PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Crystal structure analysis of LeuT complexed with L-alanine, sodium, and clomipramine

Release Data :

2007-08-21

Compound :

mol_id	molecule	chains
1	Transporter	A

Source :

mol_id	organism_scientific	expression_system
1	Aquifex aeolicus (taxid:224324)	Escherichia coli (taxid:562)
	strain: VF5 gene: snf expression_system_strain: C41(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: pET16b

Authors :

Singh, S.K., Yamashita, A., Gouaux, E.

Keywords :

membrane protein, neurotransmitter sodium symporter, occluded, tricyclic antidepressant, inhibitor, Transmembrane, Transport, TRANSPORT PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.85 Å )

Citation :

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.

Singh, S.K.,Yamashita, A.,Gouaux, E.
(2007) Nature 448 : 952 - 956

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

Yamashita, A.,Singh, S.K.,Kawate, T. et al.
(2005) Nature 437 : 215 - 223

PDB ID: 2QEI