Het-PDB Navi2 (PDB: 2Q3I)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CL	Chloride ion				PoSSuM

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
ACE	Acetyl group

Download interaction data: 2Q3I

Code :

2Q3I PDBj RCSB PDB PDBe

Header :

VIRAL PROTEIN/INHIBITOR

Title :

Crystal structure of the D10-P3/IQN17 complex: a D-peptide inhibitor of HIV-1 entry bound to the GP41 coiled-coil pocket

Release Data :

2007-06-12

Compound :

mol_id	molecule	chains
1	Fusion protein between the Coiled-Coil pocket of HIV GP41 and gcn4-PIQI	A

mol_id	molecule	chains
2	D-peptide	D

Source :

mol_id	organism_scientific
1
	synthetic: yes other_details: Peptide synthesis. GCN4-HIV gp41 fusion, called IQN17. The sequence naturally occurs in Saccharomyces cerevisiae and human immunodeficiency virus

mol_id	organism_scientific
2
	synthetic: yes other_details: Peptide synthesis. D-peptide found by screening.

Authors :

Malashkevich, V.N., Eckert, D.M., Hong, L.H., Carr, P.A., Kim, P.S.

Keywords :

envelope glycoprotein, VIRAL PROTEIN-INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 1.50 Å )

Citation :

Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket

Eckert, D.M.,Malashkevich, V.N.,Hong, L.H. et al.
(1999) Cell(Cambridge,Mass.) 99 : 103 - 105

Crystal Structure of GCN4-Piqi, a Trimeric Coiled-Coil with Buried Polar Residues.

Eckert, D.M.,Malashkevich, V.N.,Kim, P.S.
(1998) J.Mol.Biol. 284 : 859 - 865

Core structure of gp41 from the HIV envelope glycoprotein

Chan, D.C.,Fass, D.,Berger, J.M. et al.
(1997) Cell(Cambridge,Mass.) 89 : 263 - 273

PDB ID: 2Q3I