Brand  (β version)

PDB ID: 2PJ0

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ZN Zinc ion PoSSuM
922 (5r,6s,8s)-8-(3-{[amino(imino)methyl]amino}phenyl)-6-hydroxy-5-isopropyl-3-oxo-1-phenyl-2,7-dioxa-4-aza-6-phosphanonan-9-oic acid 6-oxide PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 2PJ0   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B [((R)-1-Benzyloxycarbonylamino-2-methyl-propyl)-hydroxy-phosphinoyloxy]-(3-guanidino-phenyl)-acetic acid COMPLEX
Release Data : 2008-01-22
Compound :
mol_id molecule chains
1 Carboxypeptidase B A,B,C
ec: 3.4.17.2
fragment: CATALYTIC DOMAIN
Source :
mol_id organism_scientific organism_common
1 Sus scrofa  (taxid:9823) Pig
Authors : Adler, M., Whitlow, M.
Keywords : CARBOXYPEPTIDASE B, EXOPEPTIDASE, Phosphinate BASED INHIBITOR, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.65 Å )
Citation :

Structures of potent selective peptide mimetics bound to carboxypeptidase B.

Adler, M.,Buckman, B.,Bryant, J.  et al.
(2008)  Acta Crystallogr.,Sect.D  64 : 149 - 157

PubMed: 18219114
DOI: 10.1107/S0907444907057228

Crystal Structures of Potent Thiol-Based Inhibitors Bound to Carboxypeptidase B.

Adler, M.,Bryant, J.,Buckman, B.  et al.
(2005)  Biochemistry  44 : 9339 - 9347

3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa).

Islam, I.,Bryant, J.,May, K.  et al.
(2007)  Bioorg.Med.Chem.Lett.  17 : 1349 - 1354

Reaction

Chain : A, B, C
UniProt : P09955 (CBPB1_PIG)
Reaction: EC: Evidence:
Physiological Direction:
Preferential release of a C-terminal lysine or arginine amino acid. 3.4.17.2 UniProtKB:P00732
-